I've been using this stuff faithfully every night for about 5 years, and I can say that although the results are subtle, they are there. I started when I noticed dark and/or glossy lip products feathering in the tiny vertical lines around my lips- the vermillion border, since I've always wanted to throw that into a sentence :) I read up on lip treatments, and was interested in the PTR product specifically because of the high percentage of peptides in the ingredient list. I'm not sure that there is a huge amount of data on peptides as a proven treatment for fine lines and wrinkles, but it's better than being charged an arm and a leg for a product that only moisturizes, and there is at least some published material that suggests a degree of efficacy in the role of topical peptides as an anti-aging treatment. At any rate, the fine lines around my mouth are effectively non-existent now, and I no longer have any issue with lip products feathering. If this product *didn't* work, you'd expect at least no change, if not an outright increase in lines after 5 years. Of course, there is no plumping effect, but if you expect a topical product to change the shape of your mouth, you need to check your expectations anyway. It's not extremely moisturizing, but I usually counter this by slathering on some occlusive balm over it before going to bed. My only other complaint is that it's very difficult to tell how much is left in the pump, and suspect that quite a bit of product is left when the pump goes out. It would be nice if there was a clear plastic window to see the level of product left, but since I'm otherwise happy with the product, I just knocked a lippie off the packaging score. I do appreciate the airtight pump, and consider the packaging issue to be very minor.