I have been using Phloretin CF consistently for about two and a half months. After the first two weeks, I noticed my skin felt and looked better. It had that "glow" that is described in many reviews. However, my skin began to get very sensitive to the product, specifically near my eyes. It dried the skin out, along with making the skin have a burning sensation which was quite painful and uncomfortable. I had to let my skin "breathe" for about a week before I continued use. After about a month of use, I began using it on my neck. My neck had the same reaction as the skin near my eyes - except worse. It grew red, dry, and very painful, even when not touching it. I contemplated discontinuing use all together. Again, I let the skin on my neck rest for a week before I ultimately decided to continue use. After the reactions to both the skin around my eyes and on my neck, it made the wrinkles I do have (FYI: I am 30 years old) appear worse and more pronounced. I assume this is from the drying properties of the product. I read lots of reviews following this, and the big factor that stuck out was to apply to a DRY face. I was applying right after washing my face in the morning and it was not completely dry, and I believe that contributed to the reactions I had. Also, I was applying it too close to the skin around my eyes - I make sure to apply only to my forehead, sides of my face, cheeks, around my mouth, and chin (neck and chest also). My skin has since gotten used to this regime, but I can't help but to notice that the deep wrinkles in my neck look more pronounced now than ever. I am hoping that this will smooth out over time after continued use. Although I have only been using this product for a relatively short amount of time, I think I would continue to use it despite my early experiences with it. I dove right into this product without really trying anything else because of it's high reputation. It is very costly, but it is so powerful that you do not need to use a lot and a bottle will last for quite a while. It is a huge investment, and I recommend getting trial pack (I ordered one from Amazon for about $30) before doling out big bucks for the full size bottle. I use this product in conjunction with a moisturizer that contains SPF and Azulen paste in the morning. At night, I use SkinCeuticals retinol mixed with my regular moisturizer every other night (still in search for a good eye cream). I aim to check back in around the 6 month mark after I have used this for a longer period of time to add to my review (hence why I only gave this product 3 stars at this point in time). I hope this was helpful, especially to those of you who have had reactions to early use of this product.