My dermatologist prescribed me this since i have hyperhydrosis. I was told to apply this to clean, dry armpits - and to use a hairdryer to blowdry my pits if need be. Then apply the Drysol and put plastic wrap over it and socks in my pits to hold it there close to the body. This method is too annoying for me. I now just apply it & then blowdry it dry to reduce irritation/itching. I find the itching it causes when i don't blow dry it will keep me awake. It's really annoying. To eradicate perspiration you need to apply this several times a week. Initially it usually cause irritation & redness for me. It's also recommended to do this on not recently shaved areas - so don't shave the day you use it. Besides it being a multi-step product, it still is awesome and I should try to use it more. I do recommend it, as it works better than any antiperspirant you can buy.