77 reviews

79% would repurchase

Package Quality: 3.4

Price: $$$

Package Quality: 3.4

Price: $$$


clindamycin phosphate 1.2% and tretinoin 0.025%

on 9/17/2015 12:05:00 AM

Age: 19-24

Skin: Acne-prone, Tan, Not Sure

Hair: Black, Other, Other

Eyes: Brown

Almost three months on this product and my skin has done a complete turnaround! I don't have anymore bumps that are "under my skin" that are more dominant when I wear foundation. I do have about two whiteheads and a nodule on my face, but overall my skin is smooth and my skin tone is evening out. Will update to see if it gets better or worse after the three month mark.

on 9/7/2015 3:41:00 PM

Age: 36-43

Skin: Combination, Fair, Not Sure

Hair: Brown, Other, Other

Eyes: Brown

I have both acne and fine lines. I look way younger than my age and that's probably a combination of really oily skin (STILL, at my age!) and Asian genetics, but I don't look like I'm in my 20s anymore, if you know what I mean. I have very sensitive skin as well as being acne-prone. I used this faithfully for about 8-10 months and finally gave up because it NEVER cleared up my skin, and actually just constantly triggered breakouts. It did help with fine lines and definitely helped get rid of dead skin cells, but I always, always, always had breakouts, and more than I normally have. My skin was definitely more sensitive to other treatments which has its pros and cons, but I had to be really careful in the winter about excessive flaking and sensitivity. I'm going to say that there might be an element of user error here because I don't think I ever waited 20 minutes after washing my face to apply this, and so perhaps breakouts are just my sensitive skin's reaction to something that is too harsh. I might try this again later with the "waiting 20 minutes" technique, but only after trying another Tretinoin product first. I'm not sure what to try because Retin-A contains Isopropryl Myristate which is a major pore clogger; I'll have to find a gel form or something that doesn't contain that ingredient.

on 8/14/2015 1:40:00 AM

Age: 19-24

Skin: Acne-prone, Olive, Not Sure

Hair: Brunette, Straight, Medium

Eyes: Brown

I am 23 years old and never experienced acne in my lifetime until I started to wear face makeup then I broke out all over my cheek in small skin colored bumps (clogged pores) and I developed what I would consider mild acne. I went to the derm and was prescribed minocyclin antibiotic pill along with ziana. Minocyclin did not seem to make a difference but after using ziana for a few weeks I noticed a drastic change in my skin. My skin's texture got incredibly smooth and soft and it got rid of all of those skin colored bumps. I do get the occasional pimple every now and then but I swear by this gel! I apply it before moisturizer at night about a pea size and smooth it all over my face.

on 7/16/2015 12:24:00 PM

Age: 25-29

Skin: Dry, Fair-Medium, Warm

Hair: Blond, Kinky, Fine

Eyes: Brown

I developed late onset acne around 24. I developed sever acne on my back and at first only the rare pimple on my face and tiny, hard, skin-colored bumps above my brow. I thought they were a reaction to a brow wax, but they just multiplied and would not go away. I went to my first derm. and she said it was keratin buildup. She gave me this stuff and said it works like an "topical exfoliant". After a few days, they disappeared. She prescribed Salvax for my back and let me tell you, after a few applications that stuff works wonders!! love it.


Now a year later I am getting tiny painful zits on my hairline, around my jaw, above my brows, and the occasional breakout on my upper back. The ones on my face are rarely large enough to pop, but they just sit there for days on end painful and bright red. So I went to a different derm. (for other reasons) and she prescribed this stuff again. (I refilled it not realizing it was the same medicine.- I was slightly annoyed). I applied pea sized amounts every other day and used my sensitive skin moisturizer like she prescribed. After 3 uses my cheeks started to peel and turned red. I thought I was developing rosacea or psoriasis! I discontinued use and my skin just got worse and worse. After a week the patches went away, but I am nervous to use again. I still have my breakouts- especially around my hairline, but having bright red cheeks with dry patches is much worse. I can't decide if it's worth it..

I was hoping the retinol would be an added benefit. The derm. said it would help deminish my fine lines and reduce pore, but I don't think it would be strong enough for that...

1 out of 1 people found this review helpful.

Age: 18 & Under

Skin: Combination, Fair-Medium, Not Sure

Hair: Brunette, Other, Other

Eyes: Brown

A year ago this worked amazing. My face cleared up and my pores shrunk significantly. After my face cleared up I figured I could stop using it and for a few months my skin was great. I thought all my problems were solved then it began...the worst breakouts of my life. Never before had I gotten breakouts on my cheeks or chest until then. So I went back to the dermatologist and he prescribed this again. While it did clear my skin a little I still experience more breakouts than before my previous use of this product.

1 out of 1 people found this review helpful.

on 3/16/2015 2:09:00 PM

Age: 25-29

Skin: Other, Other, Not Sure

Hair: Other, Other, Other

Eyes: Other

Let me first say that I don't usually review products, in fact, I think this will be my first review. The reason why I decided to share my thoughts with everyone is because I suffered from terrible cystic-like acne on my forehead which, even when I didn't touch them, left dark marks. After spending hundreds of dollars on skin care products and peels, I finally went to see my GP who prescribed me with Biacna (the Canadian version of Ziana).

. Initially, as other reviews had said, I broke out like crazy. I went from having a few random cystic acne to having them all over my forehead. Unfortunately, this lasted about two weeks. I also started off using the product nightly as i didn't notice a burning. So despite the purge, I encourage everyone to be patient. I also notice my skin became extra sensitive. It burned from sweating at the gym to trying my face with a town after washing it. Also, as they note on the packaging, do not use the product on the creases of your nose, upper-lip, eyes. The skin around those areas are very sensitive. I used it on my upper lip and it started peeling and drying out. I also use a moisturizer on top of the product which is nice for the extra moisture.

Now the verdict. I've been using the product now for almost 2 months, and my face is clear! However, I do get a few tiny bumps here and there but usually around my cycle. These are much more manageable compared to the cystic, painful, scaring acne. Also, when you do get a small pimple, the Biacna clears it right up in a giffy. So right now I'm at that stage where my skin is great and I'm just waiting for all the dark post-acne scars to go away, which I hope will come over the next few months. If they do, I will write a follow-up post in 2 months or so.

Good luck and be patient!

1 out of 1 people found this review helpful.

on 3/9/2015 3:07:00 AM

Age: 36-43

Skin: Acne-prone, Other, Not Sure

Hair: Blond, Other, Other

Eyes: Green

Ziana definitely improve my acne quite a bit but I still had breakouts. Using it more than once a day at the beginning was too much for my skin and caused really bad breakouts. My dermatologist suggested only using a twice a week and it works very nicely now. I've gone off of two other topical antibiotics and a pill since I have been on Ziana. I have been using it for about four years now and hope I can always afford it!

on 1/23/2015 9:09:00 PM

Age: 19-24

Skin: Oily, Medium, Not Sure

Hair: Blond, Other, Fine

Eyes: Blue

Prescribed this along with an antibiotic for my acne - lots of it on my chin and cheeks, leaving red/brown spots on my naturally porcelain skin. My skin has cleared up so much - it is naturally very oily so I didn't feel like I was drying out too much at all. Smells like fried food and a little goes a long way!

on 12/2/2014 3:59:00 PM

Age: 19-24

Skin: Combination, Medium Brown, Not Sure

Hair: Black, Wavy, Medium

Eyes: Brown

So i was prescribed Biacna (Ziana in the US) along with a antibiotic, Doxycline, for my moderate acne. So far it's been a week with both and i really haven't noticed much of a difference. I've tried eeeeeeeeeverything and i'm really hoping this works! I'll keep you guys updated :)

After 3 weeks :
So my little red spots have been slowly dissipating which should excite me, but after originally not having no active pimples some have popped up. I made the mistake of popping one and it left a mark which led to scab which i had to deal with for a good couple of days. DO NOT POP YOUR PIMPLES ON BIACNA/ZIANA YOUR SKIN IS SUPER SENSITIVE. I'm not sure if this is the purging that i've heard about but if you're anything like me, its SUPER hard not to pop them. My skin does get dry still but a lot less than originally. DO NOT WAX YOUR EYEBROWS ON THIS - Threading won't hurt your skin as much as waxing and i've heard of some horrible stories about women waxing their eyebrows while using this and getting burned or having their skin ripped off so BE CAREFUL.

After a month:
I feel like my acne is coming back. It might be the purge phase because i've been getting a bunch of white heads but i feel like they are new, not the ones sitting under the skin, I'm gonna keep going just as planned because i've heard of it taking almost the full 3 months till they start working.

Lots of love,
Shanii :)

on 7/10/2014 10:30:00 PM

Age: 19-24

Skin: Combination, Fair, Warm

Hair: Brunette, Straight, Medium

Eyes: Brown

I went to the dermatologist about a month ago to see if I could get some Retin-A for my post inflammatory hyper-pigmentation (PIH), however I also had some active acne lesions as well so she prescribed Aczone in the morning and Biacna (Ziana is the US version) at night. I have noticed that this combination has been working very well.

The Biacna has smoothed out my skin and I no longer have those little bumps under my skin like I used to - it seems to be controlling my hormonal acne. I have fewer breakouts and ones that do occur don't seem to last very long. I'll update again in a few months :)

I have to update and say that the acne has been coming back and then going away (probably with my cycle) but I havent had any cystic acne which is great - mostly white heads. I cant seem to get rid of these darn things. I'll update again in a few more months to see how things are going.

Holy crap... I haven't had a pimple in 2 weeks! Even around time of the month.. nothing.. I think the treatment is finally working. No white heads, no cysts just clear skin. I think everyone that is using this should persevere and keep going. I'll update if anything changes but right now I'm super happy!! Hyperpigmentation seems to be clearing up nicely too!

Bottom line:


It will work after about 3 months, so don't expect miracles after a week. Be patient and your skin will thank you for it.

The treatment is STILL working. I am so pleased. My hyperpigmentation is almost gone and I think it is due to the dual action of this product. It took about 3-4 months for this product to work fully, so don't give up! It's really nice to finally have the skin I had when I was in my teens (never had acne in my teen years) :)

It's July now, and I thought I'd give a review about this product. My acne DID come back unfortunately, which is why I have to lower my stars for this product. I have not had ANY cystic acne however, only the pustules. I have been trying out spearmint tea in combination with this product and it seems to be working. If you'd like to check out my reviews just search for "Spearmint Tea" here on Makeupalley.

5 out of 5 people found this review helpful.

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