I normally use Kinerase but on a whim decided to try this as it also contains the anti-aging extract, kinetin. Dermaquest cream is lightweight and did not cause my combo skin to break out. I did not notice any difference between using this and Kinerase. I primarily use products containing kinetin because it is soothing to my easily irritated skin. Dermaquest also contains CoQ10, aloe vera, wheat protein, glucosamine and green tea extract. Won't repurchase because I prefer Kinerase Clear Skin lotion. Paraben free.